Background: The N-terminal pro-brain natriuretic peptide (Nt-proBNP) is a marker of cardiac dysfunction. This study aimed to detect the association of
a natural pro-brain natriuretic peptide with renal impairment parameters in Egyptian type 2 in diabetic patients with microangiopathy.
Methods: We evaluated the Nt-proBNP levels 94 types 2 diabetic patients with and without microangiopathy and correlate them with various patients' physical and biochemical parameters.
Results: Nt-proBNP levels were significantly correlated with renal impairment parameters.
Conclusions: Nt-proBNP levels assessment in diabetic patients with microangiopathy may have an important role in detecting the early stage of diabetic
nephropathy so that enables the prevention of its development and progression.
Keywords: Type 2 Diabetes Mellitus, Nt-proBNP, and Nephropathy.