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MSD Global Journal of Cancer Therapy, Immunotherapy and Radiology

Case Report       Open Access      Peer-Reviewed

A Rare Presentation of Metastatic Breast Carcinoma to the Thyroid Three Years after Mastectomy: A Case Report

Mohammed Al Duhileb* Breast and Endocrine Oncology Surgeon, King Fahad Specialist Hospital- Dammam, Saudi Arabia.

Introduction: Breast cancer is the most common cancer in women. Yet, metastasis to the thyroid is a rare occurrence. Here we present the case of a patient with breast cancer metastasis to the thyroid gland to discuss the management of such presentations compared to the current literature. We also present this case to add to the existing literature and aid in the expansion and better understanding of rare incidences as such.

Presentation of Case: A 38-year-old female with no chronic medical illnesses was diagnosed with. invasive ductal carcinoma of the right breast T3N0M0 in 2017. Chemotherapy consists of eight cycles of neoadjuvant chemotherapy followed by a simple mastectomy, sentinel lymph node biopsy, and adjuvant radiation to the chest wall. The patient has been on hormonal therapy since diagnosis. In 2020, the patient presented with a left neck mass and underwent a total thyroidectomy. Pathological analysis of the specimen confirmed the presence of poorly differentiated cells consistent with mammary ductal cells while the right thyroid lobe demonstrated features of papillary thyroid carcinoma.

Conclusion: Intrathyroidal metastasis of extrathyroidal cancers is rare but should be considered when patients are present with a history of cancer. Thyroidectomies in isolated secondary thyroid cancers have been shown to prolong the disease-free period but are not a definitive cure.

Keywords: Case Report, Breast Cancer, Metastases, Thyroid Cancer.

 

Introduction

Breast cancer is the most common cancer in women. It frequently metastasizes to the lungs, bone, liver, and brain. Yet, metastasis to the thyroid is a rare occurrence with an incidence rate of 0.02-1.4% [1, 2]. As a result, the literature is scarce and there is no proven way on the best management plan. Here we present the case of a patient with breast cancer metastasis to the thyroid gland three years after the completion of her treatment of breast carcinoma followed by a discussion of the management of secondary thyroid cancer compared to the current literature.

Presentation of Case

This is a case of a 38-year-old Saudi female who presented to the breast clinic with a right breast mass in 2017 for one year with no other symptoms and no risk factors for breast cancer. Her past medical and surgical history were not signi????icant. Her medication history, psychosocial history, and family history were unremarkable....... 

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