Vijay Soni
Postdoctoral Associate
- Email:sonivijay07@gmail.com
- Department:Department of Medicine
- University:Weil Cornell Medicine,
- Country:New York, USA
Biography:
Vijay Soni, Ph.D. Postdoctoral Associate, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA. Education Degree Year of passing Board/ University Percentage Remarks Postdoctoral Associate From June 2016 Weil Cornell Medicine, New York, U.S.A Pursuing Till date PhD 2016 National Institute of Immunology, New Delhi and BITS-Pilani, Hyderabad campus. Title: Study of M.tb. GlmU. Awarded M.Sc. Biotechnology 2009 Mohan Lal Sukhadia University, Udaipur, India 72.33% Qualified 29/5/2009 B.Sc. Biology 2006 Mohan Lal Sukhadia University, Udaipur, India 76.29% Qualified 15/06/2006 Research Experience and Interest.
I have total 9 years of research experience which includes 3 years of my postdoctoral research work. Since 2010, I am working in the field of microbiology, drug development, and immunology. During my Ph.D. (2012 to 2016) I have worked on Mycobacterium tuberculosis cell wall protein (GlmU) and characterized it as a best therapeutic target to cure tuberculosis (TB). Soon after that I have joined Weill Cornell Medical College, New York in June 2016 and working in the field of metabolomics to understand the immunological insults and adaptations happening during TB infection.
I have identified various metabolic signatures and an important mechanism to enhance the therapeutic potential of anti-TB drugs and therapies. I am good at scientific idea identification, metabolomics data analysis, database preparation, identifying new drug targets with the help of metabolomics and genetic engineering etc. I am expert in microbiology, genetic engineering, metabolomics, molecular biology, drug target identification, drug screening, drug development, in vivo drug testing and identification of metabolic bio-signature (Biomarkers) for better diagnosis. Ph.D. Research … Ph.D. work: Study of Mycobacterium tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmUMtb).
For my Ph.D. research, I was involved in investigating and establishing GlmUMtb and UDPGlcNAc biosynthesis pathway as a candidate for intervention measures against established tuberculosis infections. GlmUMtb is a bi-functional enzyme engaged in the synthesis of two metabolic intermediates N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and UDP-GlcNAc, catalyzed by the C- and N-terminal domains respectively. UDP-GlcNAc is a key metabolite essential for the synthesis of peptidoglycan, disaccharide linker, arabinogalactan, and mycothiols.
During five and half years of my doctoral studies, I was involved in structure and functional analysis of GlmUMtb and determined the detail catalytic mechanism of acetyltransferase activity and phosphorylation site. In 2012, this collaborative effort with Dr. Balaji Prakash’s group was published in J. Biological Chemistry, in which I was the co-first author.
Research Interests:
I am expert in microbiology, genetic engineering, metabolomics, molecular biology, drug target identification, drug screening, drug development, in vivo drug testing and identification of metabolic bio-signature (Biomarkers) for better diagnosis.